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Common irritants that are essential causes of occupational dermatitis (tailored from <>6, 66, 188]) Water and its additives (Salts and oxides of calcium, magnesium, and iron) Skin cleansers Soaps, detergents, “waterless cleansers, ”and components (sand, silica) Industrial cleansing Detergents, surface-lively brokers, brokers sulfonated oils, wetting brokers, emulsifiers, enzymes Alkalis Soap, soda, ammonia, potassium and sodium hydroxides, cement, lime, sodium silicate, trisodium phosphate, and numerous amines Acids Severe irritancy (caustic): sulfuric, hydrochloric, nitric, chromic, and hydrofluoric acids Moderate irritancy: acetic, oxalic, and salicylic acids Oils Cutting oils with various additives (water, emulsifiers, antioxidants, anticorrosive agents, preserva- tives, dyes and perfumes) Lubricating and spindle oils Organic solvents White spirit, benzene, toluene, trichloroethylene, perchloroethylene, methylene chloride, chloro- benzene Methanol, ethanol, isopropanol, propylene glycol Ethyl acetate, acetone, methyl ethyl ketone, ethylene glycol monomethyl ether, nitroethane, turpen- tine, carbon disulfide Thinners (mixtures of alcohols, ketones, and toluene) Oxidizing agents Hydrogen peroxide, benzoyl peroxide, cyclohexanone peroxide, sodium hypochlorite Reducing agents Phenols, hydrazines, aldehydes, thioglycolates Plants Citrus peel and juice, flower bulbs, garlic, onion, pineapple, pelargonium, iris, cucumbers, butter- cups, asparagus, mustard, barley, chicory, corn Various plants of the spurge family (Euphorbiaceae), Brassicaceae household (Cruciferae) and Ranun- culaceae family (for further details see <>1]) Animal products Pancreatic enzymes, bodily secretions Miscellaneous irritants Alkyl tin compounds and penta-, tetra-, and trichlorophenols (wooden preservatives) Bromine (in gasoline, agricultural chemicals, paper industry, flame retardant) Methylchloroisothiazolinone and methylisothiazolinone (irritant at excessive concentrations throughout manufacturing or misuse) Components of plastic processing (formaldehyde, phenol, cresol, styrene, di-isocyanates, acrylic monomers, diallyl phthalate, aliphatic and fragrant amines, epichlorohydrin) Metal polishes Fertilizers Propionic acid (preservative in animal feed) Rust-preventive merchandise Paint removers (alkyl bromide) Acrolein, crotonaldehyde, ethylene oxide, mercuric salts, zinc chloride, chlorine 262 Peter J. 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